Chemicals and Drugs

Proto-Oncogene Proteins c-maf

Maf proto-oncogene protein is the major cellular homolog of the V-MAF ONCOGENE PROTEIN. It was the first of the mammalian MAF TRANSCRIPTION FACTORS identified, and it is induced in activated T-LYMPHOCYTES and regulates GENETIC TRANSCRIPTION of INTERLEUKIN-4. c-maf is frequently translocated to an immunoglobulin locus in MULTIPLE MYELOMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Maf proto-oncogene protein is the major cellular homolog of the V-MAF ONCOGENE PROTEIN. It was the first of the mammalian MAF TRANSCRIPTION FACTORS identified, and it is induced in activated T-LYMPHOCYTES and regulates GENETIC TRANSCRIPTION of INTERLEUKIN-4. c-maf is frequently translocated to an immunoglobulin locus in MULTIPLE MYELOMA.

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Synonyms

12 entry terms
  • Proto-Oncogene Protein c-maf
  • c-maf Protein
  • c-maf Proto-Oncogene Protein
  • maf Proto-Oncogene Protein
  • Proteins c-maf, Proto-Oncogene
  • Proto Oncogene Protein c maf
  • Proto Oncogene Proteins c maf
  • Proto-Oncogene Protein, c-maf
  • Proto-Oncogene Protein, maf
  • c-maf, Proto-Oncogene Protein
  • c-maf, Proto-Oncogene Proteins
  • maf Proto Oncogene Protein

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30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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History Note

2006(1994)

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References

  1. National Library of Medicine. Proto-Oncogene Proteins c-maf. Medical Subject Headings (MeSH). 2026. Unique ID D051257. http://id.nlm.nih.gov/mesh/2026/D051257
  2. Proto-Oncogene Proteins c-maf. In: Wikidata. https://www.wikidata.org/wiki/Q58622319