Chemicals and Drugs

Protein Kinase C beta

PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.

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Classification

Broader headings

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Synonyms

16 entry terms
  • PKC(beta)
  • PKC beta 1
  • PKC beta 2
  • PKC-beta II
  • PKCB1
  • PKCBII
  • PKCbeta2
  • Protein Kinase C beta I
  • Protein Kinase C beta II
  • Protein Kinase C beta1
  • Protein Kinase C beta2
  • Protein Kinase C-beta (II)
  • Protein Kinase C-beta(II)
  • PKC beta II
  • beta 1, PKC
  • beta 2, PKC

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Protein Kinase C beta. Medical Subject Headings (MeSH). 2026. Unique ID D064546. http://id.nlm.nih.gov/mesh/2026/D064546
  2. Protein Kinase C beta. In: Wikidata. https://www.wikidata.org/wiki/Q21114850