Chemicals and Drugs

Protein Kinase C-epsilon

A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.

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Classification

Broader headings

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Synonyms

5 entry terms
  • PKC epsilon
  • PKC-epsilon Serine Threonine Kinase
  • Protein Kinase C epsilon
  • Kinase C-epsilon, Protein
  • PKC epsilon Serine Threonine Kinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1994)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Protein Kinase C-epsilon. Medical Subject Headings (MeSH). 2026. Unique ID D051744. http://id.nlm.nih.gov/mesh/2026/D051744
  2. Protein Kinase C-epsilon. In: Wikidata. https://www.wikidata.org/wiki/Q24769981