Chemicals and Drugs

Protein Inhibitors of Activated STAT

A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.

MeSH Record

Classification

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MeSH Record

Synonyms

6 entry terms
  • PIAS Proteins
  • PIAS1 Protein
  • PIAS1 Protein Inhibitor of Activated STAT
  • PIAS2 Protein Inhibitor of Activated STAT
  • PIAS3 Protein Inhibitor of Activated STAT
  • PIAS4 Protein Inhibitor of Activated STAT

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1998)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Protein Inhibitors of Activated STAT. Medical Subject Headings (MeSH). 2026. Unique ID D050828. http://id.nlm.nih.gov/mesh/2026/D050828
  2. Protein Inhibitors of Activated STAT. In: Wikipedia. https://en.wikipedia.org/wiki/Protein_inhibitor_of_activated_STAT
  3. Protein Inhibitors of Activated STAT. In: Wikidata. https://www.wikidata.org/wiki/Q83164260