Chemicals and Drugs

Protein D-Aspartate-L-Isoaspartate Methyltransferase

A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTIC ACID and D-ASPARTIC ACID residues in peptides and proteins. It initiates the repair of proteins damaged by the spontaneous decomposition of normal L-aspartic acid and L-asparagine residues.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTIC ACID and D-ASPARTIC ACID residues in peptides and proteins. It initiates the repair of proteins damaged by the spontaneous decomposition of normal L-aspartic acid and L-asparagine residues.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

41 entry terms
  • D-Aspartyl-L-Isoaspartyl Methyltransferase
  • Isoaspartyl-Aspartyl Protein Methyltransferase
  • L-Isoaspartyl Protein Carboxymethyltransferase
  • Methyltransferase PIMT
  • PCMT1 Gene Product
  • Protein L-Isoaspartate O-Methyltransferase
  • Protein L-Isoaspartyl Methyltransferase
  • Protein-D-Asp Methyltransferase
  • Protein-D-Aspartate Methyltransferase
  • Protein-L-Isoaspartate Methyltransferase
  • Protein-L-Isoaspartate-D-Aspartate-O-Methyltransferase
  • Protein-beta-Aspartate Methyltransferase
  • pcm Gene Product
  • Carboxymethyltransferase, L-Isoaspartyl Protein
  • D Aspartyl L Isoaspartyl Methyltransferase
  • Gene Product, PCMT1
  • Gene Product, pcm
  • Isoaspartyl Aspartyl Protein Methyltransferase
  • L Isoaspartyl Protein Carboxymethyltransferase
  • L-Isoaspartate O-Methyltransferase, Protein
  • L-Isoaspartyl Methyltransferase, Protein
  • Methyltransferase, D-Aspartyl-L-Isoaspartyl
  • Methyltransferase, Isoaspartyl-Aspartyl Protein
  • Methyltransferase, Protein D-Aspartate-L-Isoaspartate
  • Methyltransferase, Protein L-Isoaspartyl
  • Methyltransferase, Protein-D-Asp
  • Methyltransferase, Protein-D-Aspartate
  • Methyltransferase, Protein-L-Isoaspartate
  • Methyltransferase, Protein-beta-Aspartate
  • O-Methyltransferase, Protein L-Isoaspartate
  • PIMT, Methyltransferase
  • Protein Carboxymethyltransferase, L-Isoaspartyl
  • Protein D Asp Methyltransferase
  • Protein D Aspartate L Isoaspartate Methyltransferase
  • Protein D Aspartate Methyltransferase
  • Protein L Isoaspartate D Aspartate O Methyltransferase
  • Protein L Isoaspartate Methyltransferase
  • Protein L Isoaspartate O Methyltransferase
  • Protein L Isoaspartyl Methyltransferase
  • Protein Methyltransferase, Isoaspartyl-Aspartyl
  • Protein beta Aspartate Methyltransferase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002; use PROTEIN D-ASPARTATE-L-ISOASPARTATE METHYLTRANSFERASE (NM) 1984-2001

MeSH Record

Previous Indexing

  • Protein Methyltransferases (1984-2001)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Protein D-Aspartate-L-Isoaspartate Methyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D026601. http://id.nlm.nih.gov/mesh/2026/D026601
  2. Protein D-Aspartate-L-Isoaspartate Methyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q21105038