Chemicals and Drugs

Protein-Arginine Deiminase Type 4

A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.

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Synonyms

13 entry terms
  • PAD V Enzyme
  • PADI4 Protein
  • PADI5 Protein
  • Peptidyl Arginine Deiminase Type 4
  • Peptidyl Arginine Deiminase Type IV
  • Peptidylarginine Deiminase IV
  • Peptidylarginine Deiminase Type 4
  • Peptidylarginine Deiminase Type IV
  • Peptidylarginine Deiminase V
  • Protein Arginine Deiminase 4
  • Protein Arginine Deiminase Type 4
  • Protein Arginine Deiminase Type IV
  • Protein-Arginine Deiminase Type IV

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2020 (2004)

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AMA Style

References

  1. National Library of Medicine. Protein-Arginine Deiminase Type 4. Medical Subject Headings (MeSH). 2026. Unique ID D000080002. http://id.nlm.nih.gov/mesh/2026/D000080002
  2. Protein-Arginine Deiminase Type 4. In: Wikidata. https://www.wikidata.org/wiki/Q21123689