Chemicals and Drugs

Protein-Arginine Deiminase Type 2

A widely expressed isoenzyme of peptidylarginine deiminase, a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A widely expressed isoenzyme of peptidylarginine deiminase, a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner.

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Classification

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Synonyms

10 entry terms
  • PADI2 Protein
  • Peptidyl Arginine Deiminase Type 2
  • Peptidyl Arginine Deiminase Type II
  • Peptidylarginine Deiminase II
  • Peptidylarginine Deiminase Type 2
  • Peptidylarginine Deiminase Type II
  • Protein Arginine Deiminase 2
  • Protein Arginine Deiminase Type 2
  • Protein Arginine Deiminase Type II
  • Protein-Arginine Deiminase Type II

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2020

MeSH Record

Previous Indexing

  • Hydrolases (1981-2019)
  • Hydrolases (2004-2019)
  • Protein-Arginine Deiminases (2018-2019)

MeSH Hierarchy

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References

  1. National Library of Medicine. Protein-Arginine Deiminase Type 2. Medical Subject Headings (MeSH). 2026. Unique ID D000080064. http://id.nlm.nih.gov/mesh/2026/D000080064
  2. Protein-Arginine Deiminase Type 2. In: Wikidata. https://www.wikidata.org/wiki/Q21123692