Chemicals and Drugs

Prostaglandin H2

A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins.

Chemical Identity

Chemical Information

Molecular Formula
C20H32O5
Molecular Weight
352.5 g/mol
CAS Registry No.
42935-17-1
IUPAC Name
(Z)-7-[(1R,4S,5R,6R)-6-[(E,3S)-3-hydroxyoct-1-enyl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]hept-5-enoic acid
InChIKey
YIBNHAJFJUQSRA-YNNPMVKQSA-N
SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@H]2C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)OO2)O
MeSH Unique ID
D044262
Source
PubChem CID 445049

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

2 entry terms
  • PGH(2)
  • PGH2

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/analogs: coord with PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC if pertinent

MeSH Record

History Note

2004; use PROSTAGLANDIN H2 (NM) 1980-2003

MeSH Record

Previous Indexing

  • Prostaglandin Endoperoxides, Synthetic (1986-1992)
  • Prostaglandins H (1993-2003)

MeSH Hierarchy

Tree Numbers

  1. D01w.248w.497w.158w.685w.750w.744.650.500w
  2. D01w.339w.431w.374w.744.650.500w
  3. D01w.650w.550w.750w.700.650.500w
  4. D02w.389w.593w.374w.744.650.500w
  5. D10w.251w.355w.255w.550w.025.650.500w
  6. D23.469.050w.175w.725w.025.650.500w

AMA Style

References

  1. National Library of Medicine. Prostaglandin H2. Medical Subject Headings (MeSH). 2026. Unique ID D044262. http://id.nlm.nih.gov/mesh/2026/D044262
  2. Prostaglandin H2. In: Wikipedia. https://en.wikipedia.org/wiki/Prostaglandin_H2
  3. Prostaglandin H2. In: Wikidata. https://www.wikidata.org/wiki/Q416567
  4. Prostaglandin H2. In: PubChem Compound. CID 445049. https://pubchem.ncbi.nlm.nih.gov/compound/445049