Chemicals and Drugs

Propantheline

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.

Chemical Identity

Chemical Information

Molecular Formula
C23H30NO3+
Molecular Weight
368.5 g/mol
CAS Registry No.
298-50-0
IUPAC Name
methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
InChIKey
VVWYOYDLCMFIEM-UHFFFAOYSA-N
SMILES
CC(C)[N+](C)(CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13)C(C)C
MeSH Unique ID
D011413
Source
PubChem CID 4934

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Pro-Banthine
  • Probanthine
  • Propantheline Bromide
  • Bromide, Propantheline
  • Pro Banthine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

81; was see under METHANTHELINE 1963-67; PROPANTHELINE BROMIDE was heading 1964-80 (Prov 1964-71)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Propantheline. Medical Subject Headings (MeSH). 2026. Unique ID D011413. http://id.nlm.nih.gov/mesh/2026/D011413
  2. Propantheline. In: Wikidata. https://www.wikidata.org/wiki/Q3275451
  3. Propantheline. In: PubChem Compound. CID 4934. https://pubchem.ncbi.nlm.nih.gov/compound/4934