Structured Summary
Abstract
The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.
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Synonyms
11 entry terms
- IF2 Protein
- Initiation Factor-2
- Peptide Initiation Factor 2
- Peptide Initiation Factor IF-2
- Translational Initiation Factor 2
- infB Gene Product
- infB Protein
- Initiation Factor 2
- Initiation Factor-2, Prokaryotic
- Peptide Initiation Factor IF 2
- Prokaryotic Initiation Factor 2
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003; use PROKARYOTIC INITIATION FACTOR-2 (NM) 1990-2002
MeSH Record
Previous Indexing
- Peptide Initiation Factors (1990-2002)
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AMA Style
References
- National Library of Medicine. Prokaryotic Initiation Factor-2. Medical Subject Headings (MeSH). 2026. Unique ID D039881. http://id.nlm.nih.gov/mesh/2026/D039881
- Prokaryotic Initiation Factor-2. In: Wikipedia. https://en.wikipedia.org/wiki/Bacterial_initiation_factor_2
- Prokaryotic Initiation Factor-2. In: Wikidata. https://www.wikidata.org/wiki/Q7249510