Structured Summary
Abstract
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
15 entry terms
- Palsy, Progressive Supranuclear
- Richardson's Syndrome
- Steele-Richardson-Olszewski Disease
- Steele-Richardson-Olszewski Syndrome
- Supranuclear Palsy, Progressive
- Progressive Supranuclear Palsies
- Richardson Syndrome
- Steele Richardson Olszewski Disease
- Steele Richardson Olszewski Syndrome
- Supranuclear Palsies, Progressive
- Ophthalmoplegia, Progressive Supranuclear
- Progressive Supranuclear Ophthalmoplegia
- Progressive Supranuclear Palsy 1
- Supranuclear Palsy, Progressive, 1
- Supranuclear Ophthalmoplegia, Progressive
MeSH Record
Aspects Covered
35 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
History Note
1987
MeSH Record
Previous Indexing
- Ophthalmoplegia (1979-1986)
- Paralysis (1966-1986)
- Paralysis, Bulbar (1966-1986)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
WL 358.5
AMA Style
References
- National Library of Medicine. Progressive Supranuclear Palsy. Medical Subject Headings (MeSH). 2026. Unique ID D013494. http://id.nlm.nih.gov/mesh/2026/D013494
- Progressive Supranuclear Palsy. In: Wikipedia. https://en.wikipedia.org/wiki/Progressive_supranuclear_palsy
- Progressive Supranuclear Palsy. In: Wikidata. https://www.wikidata.org/wiki/Q945930