Chemicals and Drugs

Progesterone Reductase

An enzyme that catalyzes the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione. EC 1.1.1.145.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione. EC 1.1.1.145.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase
  • 5-Ene-3 beta-hydroxysteroid Dehydrogenase
  • Steroid delta(5)-3 beta-ol Dehydrogenase
  • 3 beta Hydroxy delta 5 Steroid Dehydrogenase
  • 5 Ene 3 beta hydroxysteroid Dehydrogenase
  • Dehydrogenase, 3 beta-Hydroxy-delta-5-Steroid
  • Dehydrogenase, 5-Ene-3 beta-hydroxysteroid
  • Reductase, Progesterone

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(75); was see under 3-HYDROXYSTEROID DEHYDROGENASES 1975-90

MeSH Record

Previous Indexing

  • Hydroxysteroid Dehydrogenases (1972-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Progesterone Reductase. Medical Subject Headings (MeSH). 2026. Unique ID D011375. http://id.nlm.nih.gov/mesh/2026/D011375
  2. Progesterone Reductase. In: Wikidata. https://www.wikidata.org/wiki/Q76386108