Chemicals and Drugs

Pristinamycin

An antibiotic mixture originally isolated from Streptomyces pristinaspiralis. It is a mixture of compounds from STREPTOGRAMIN GROUP A: pristinamycin IIA and IIB and from STREPTOGRAMIN GROUP B: pristinamycin IA, pristinamycin IB, pristinamycin IC.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic mixture originally isolated from Streptomyces pristinaspiralis. It is a mixture of compounds from STREPTOGRAMIN GROUP A: pristinamycin IIA and IIB and from STREPTOGRAMIN GROUP B: pristinamycin IA, pristinamycin IB, pristinamycin IC.

Chemical Identity

Chemical Information

Molecular Formula
C71H84N10O17
Molecular Weight
1349.5 g/mol
CAS Registry No.
270076-60-3
IUPAC Name
N-(3-benzyl-12-ethyl-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.06,10]hexacosan-15-yl)-3-hydroxypyridine-2-carboxamide;(12Z,17Z,19Z)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone
InChIKey
MVTQIFVKRXBCHS-FHWPYUEJSA-N
SMILES
CCC1C(=O)N2CCCC2C(=O)N(C(C(=O)N3CCC(=O)CC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C.CC1/C=C\C(=O)NC/C=C\C(=C/C(CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)OC1C(C)C)O)\C
MeSH Unique ID
D025762
Source
PubChem CID 11979535

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Pyostacine
  • RP 7293
  • RP7293

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2002; use VIRGINIAMYCIN 1994-2001; for RP7293 and RP 7293 use VIRGINIAMYCIN 1998-2001

MeSH Record

Previous Indexing

  • Virginiamycin (1994-2001)

MeSH Hierarchy

Tree Numbers

  1. D04w.345w.566w.802w.374w
  2. D12.644w.641w.802w.374w

AMA Style

References

  1. National Library of Medicine. Pristinamycin. Medical Subject Headings (MeSH). 2026. Unique ID D025762. http://id.nlm.nih.gov/mesh/2026/D025762
  2. Pristinamycin. In: Wikipedia. https://en.wikipedia.org/wiki/Pristinamycin
  3. Pristinamycin. In: Wikidata. https://www.wikidata.org/wiki/Q423412
  4. Pristinamycin. In: PubChem Compound. CID 11979535. https://pubchem.ncbi.nlm.nih.gov/compound/11979535