Diseases

Primary Hypertrophic Osteoarthropathy

A condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, SEBORRHEA; HYPERHIDROSIS; periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. Inheritance is primarily autosomal recessive, but an autosomal dominant form exists.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, SEBORRHEA; HYPERHIDROSIS; periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. Inheritance is primarily autosomal recessive, but an autosomal dominant form exists.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

29 entry terms
  • Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive
  • Idiopathic Hypertrophic Osteoarthropathy
  • Osteoarthropathy, Primary Hypertrophic
  • Pachydermoperiostosis
  • Pachydermoperiostosis, Autosomal Recessive
  • Touraine-Solente-Gole Syndrome
  • Autosomal Recessive Pachydermoperiostosis
  • Hypertrophic Osteoarthropathy, Idiopathic
  • Hypertrophic Osteoarthropathy, Primary
  • Osteoarthropathy, Idiopathic Hypertrophic
  • Recessive Pachydermoperiostosis, Autosomal
  • Touraine Solente Gole Syndrome
  • Acropachy, Hereditary
  • Clubbing of Digits
  • Cranioosteoarthropathy
  • Currarino Idiopathic Osteoarthropathy
  • Digital Clubbing, Isolated Congenital
  • Familial Idiopathic Osteoarthropathy Of Childhood
  • Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant
  • Pachydermoperiostosis, Autosomal Dominant
  • Primary Hypertrophic Osteoarthropathy, Autosomal Dominant
  • Acropachies, Hereditary
  • Autosomal Dominant Pachydermoperiostoses
  • Autosomal Dominant Pachydermoperiostosis
  • Cranioosteoarthropathies
  • Hereditary Acropachies
  • Hereditary Acropachy
  • Osteoarthropathy, Currarino Idiopathic
  • Pachydermoperiostoses, Autosomal Dominant

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

OSTEOARTHROPATHY, SECONDARY HYPERTROPHIC is also available

MeSH Record

History Note

2014(1964)

MeSH Hierarchy

Tree Numbers

  1. C05w.116w.725w
  2. C05w.550w.648w
  3. C16w.320w.718w

AMA Style

References

  1. National Library of Medicine. Primary Hypertrophic Osteoarthropathy. Medical Subject Headings (MeSH). 2026. Unique ID D010004. http://id.nlm.nih.gov/mesh/2026/D010004
  2. Primary Hypertrophic Osteoarthropathy. In: Wikipedia. https://en.wikipedia.org/wiki/Pachydermoperiostosis
  3. Primary Hypertrophic Osteoarthropathy. In: Wikidata. https://www.wikidata.org/wiki/Q7243138