Chemicals and Drugs

Prephenate Dehydrogenase

An enzyme that catalyzes the conversion of prephenate to p-hydroxyphenylpyruvate in the presence of NAD. In the enteric bacteria, this enzyme also possesses chorismate mutase activity, thereby catalyzing the first two steps in the biosynthesis of tyrosine. EC 1.3.1.12.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the conversion of prephenate to p-hydroxyphenylpyruvate in the presence of NAD. In the enteric bacteria, this enzyme also possesses chorismate mutase activity, thereby catalyzing the first two steps in the biosynthesis of tyrosine. EC 1.3.1.12.

MeSH Record

Classification

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MeSH Record

Synonyms

5 entry terms
  • Dehydrogenase, Prephenate
  • Chorismate Mutase-Prephenate Dehydrogenase
  • Chorismate Mutase Prephenate Dehydrogenase
  • Dehydrogenase, Chorismate Mutase-Prephenate
  • Mutase-Prephenate Dehydrogenase, Chorismate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with PREPHENATE DEHYDRATASE

MeSH Record

History Note

91(75); was see under OXIDOREDUCTASES 1975-90

MeSH Record

Previous Indexing

  • Cyclohexanes (1972-1974)
  • Oxidoreductases (1972-1974)
  • Pyruvates (1972-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Prephenate Dehydrogenase. Medical Subject Headings (MeSH). 2026. Unique ID D011303. http://id.nlm.nih.gov/mesh/2026/D011303
  2. Prephenate Dehydrogenase. In: Wikipedia. https://en.wikipedia.org/wiki/Prephenate_dehydrogenase_(NADP%2B)
  3. Prephenate Dehydrogenase. In: Wikidata. https://www.wikidata.org/wiki/Q3008312