Chemicals and Drugs

Prephenate Dehydratase

An enzyme that catalyzes the conversion of prephenate to phenylpyruvate with the elimination of water and carbon dioxide. In the enteric bacteria this enzyme also possesses chorismate mutase activity, thereby catalyzing the first two steps in the biosynthesis of phenylalanine. EC 4.2.1.51.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the conversion of prephenate to phenylpyruvate with the elimination of water and carbon dioxide. In the enteric bacteria this enzyme also possesses chorismate mutase activity, thereby catalyzing the first two steps in the biosynthesis of phenylalanine. EC 4.2.1.51.

MeSH Record

Classification

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MeSH Record

Synonyms

8 entry terms
  • Prephenate Hydro-lyase
  • Dehydratase, Prephenate
  • Hydro-lyase, Prephenate
  • Prephenate Hydro lyase
  • Chorismate Mutase-Prephenate Dehydratase
  • Chorismate Mutase Prephenate Dehydratase
  • Dehydratase, Chorismate Mutase-Prephenate
  • Mutase-Prephenate Dehydratase, Chorismate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with PREPHENATE DEHYDROGENASE

MeSH Record

History Note

91(75); was see under HYDRO-LYASES 1975-90

MeSH Record

Previous Indexing

  • Cyclohexanes (1970-1974)
  • Hydro-Lyases (1970-1974)
  • Pyruvates (1970-1974)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Prephenate Dehydratase. Medical Subject Headings (MeSH). 2026. Unique ID D011302. http://id.nlm.nih.gov/mesh/2026/D011302
  2. Prephenate Dehydratase. In: Wikipedia. https://en.wikipedia.org/wiki/Prephenate_dehydratase
  3. Prephenate Dehydratase. In: Wikidata. https://www.wikidata.org/wiki/Q7240653