Structured Summary
Abstract
A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
Chemical Identity
Chemical Information
- Molecular Formula
- C19H21N5O4
- Molecular Weight
- 383.4 g/mol
- CAS Registry No.
- 19216-56-9
- IUPAC Name
- [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
- InChIKey
- IENZQIKPVFGBNW-UHFFFAOYSA-N
- SMILES
- COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC
- MeSH Unique ID
- D011224
- Source
- PubChem CID 4893
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Furazosin
- Minipress
- Pratsiol
- Prazosin HCL
- Prazosin Hydrochloride
- HCL, Prazosin
- Hydrochloride, Prazosin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
86(77); was see under QUINAZOLINES 1977-85
MeSH Record
Previous Indexing
- Piperazines (1974-1976)
- Quinazolines (1974-1976)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QV 151
AMA Style
References
- National Library of Medicine. Prazosin. Medical Subject Headings (MeSH). 2026. Unique ID D011224. http://id.nlm.nih.gov/mesh/2026/D011224
- Prazosin. In: Wikipedia. https://en.wikipedia.org/wiki/Prazosin
- Prazosin. In: Wikidata. https://www.wikidata.org/wiki/Q425296
- Prazosin. In: PubChem Compound. CID 4893. https://pubchem.ncbi.nlm.nih.gov/compound/4893