Chemicals and Drugs

Polycomb Repressive Complex 2

A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.

MeSH Record

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MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Record

Previous Indexing

  • Repressor Proteins (1998-2012)
  • Transcription Factors (1997)

MeSH Hierarchy

Tree Numbers

  1. D05.500w.781w.750w
  2. D08.811w.913w.555.500w.800.200w.500.500w
  3. D12.776w.660w.235.600w.200w
  4. D12.776w.664w.235.800w.200w
  5. D12.776w.930w.780.890w.200w

AMA Style

References

  1. National Library of Medicine. Polycomb Repressive Complex 2. Medical Subject Headings (MeSH). 2026. Unique ID D063151. http://id.nlm.nih.gov/mesh/2026/D063151
  2. Polycomb Repressive Complex 2. In: Wikipedia. https://en.wikipedia.org/wiki/PRC2
  3. Polycomb Repressive Complex 2. In: Wikidata. https://www.wikidata.org/wiki/Q17125871