Structured Summary
Abstract
A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2013
MeSH Record
Previous Indexing
- Repressor Proteins (1998-2012)
- Transcription Factors (1997)
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References
- National Library of Medicine. Polycomb Repressive Complex 1. Medical Subject Headings (MeSH). 2026. Unique ID D063150. http://id.nlm.nih.gov/mesh/2026/D063150
- Polycomb Repressive Complex 1. In: Wikipedia. https://en.wikipedia.org/wiki/Polycomb_repressive_complex_1
- Polycomb Repressive Complex 1. In: Wikidata. https://www.wikidata.org/wiki/Q21102175