Chemicals and Drugs

Polidocanol

An alkyl polyglycol ether of LAURYL ALCOHOL, chemically defined as an alcohol ethoxylate having an average alkyl chain of 12–14 carbon atoms, and an ethylene oxide chain of 9 ethylene oxide units. It is used as a detergent, and medically as a local anesthetic, and as a sclerosing agent for the treatment of ESOPHAGEAL AND GASTRIC VARICES and VARICOSE VEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alkyl polyglycol ether of LAURYL ALCOHOL, chemically defined as an alcohol ethoxylate having an average alkyl chain of 12–14 carbon atoms, and an ethylene oxide chain of 9 ethylene oxide units. It is used as a detergent, and medically as a local anesthetic, and as a sclerosing agent for the treatment of ESOPHAGEAL AND GASTRIC VARICES and VARICOSE VEINS.

Chemical Identity

Chemical Information

Molecular Formula
C30H62O10
Molecular Weight
582.8 g/mol
CAS Registry No.
3055-99-0
IUPAC Name
2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
InChIKey
ONJQDTZCDSESIW-UHFFFAOYSA-N
SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
MeSH Unique ID
D000077423
Source
PubChem CID 656641

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

61 entry terms
  • Laureth 9
  • Laureth-9
  • Polidocanols
  • Aethoxysclerol
  • Aethoxysklerol
  • Aetoxisclerol
  • Atossisclerol
  • Atoxysclerol
  • Brij 30
  • Brij-30
  • Dodecyl Ethyleneglycol Monoether
  • Ethoxysclerol
  • Hydroxypolyethoxydodecane
  • Laureth
  • Laureth-1
  • Laureth-4
  • Laureth-7
  • Lauromacrogol
  • Lauromacrogol 400
  • Lauromacrogols
  • Lubrol 12A9
  • Lubrol-PX
  • Nonaethylene Glycol Monododecyl Ether
  • Nonaethyleneglycol Monododecyl Ether
  • Polyethylene Glycol Monododecyl Ether
  • Polyethylene Glycol-7-lauryl Ether
  • Polyoxyethylene 9-lauryl Ether
  • Polyoxyethylene Lauryl Ether
  • Polyoxyethylene(4) Lauryl Ether
  • Polyoxyethylene-4-dodecyl Ether
  • Polyoxyethylenedodecyl Ether
  • Tetraethylene Glycol Dodecyl Ether
  • Tetraethyleneglycol Lauryl Ether
  • Thesit
  • alpha-Dodecyl-omega-hydroxypoly(oxy-1,2ethanediyl)
  • Brij30
  • Dodecyl Ethyleneglycol Monoethers
  • Ether, Nonaethyleneglycol Monododecyl
  • Ether, Polyethylene Glycol-7-lauryl
  • Ether, Polyoxyethylene 9-lauryl
  • Ether, Polyoxyethylene Lauryl
  • Ether, Polyoxyethylene-4-dodecyl
  • Ether, Tetraethyleneglycol Lauryl
  • Ethyleneglycol Monoether, Dodecyl
  • Laureth 1
  • Laureth 4
  • Laureth 7
  • Laureths
  • Lauryl Ether, Tetraethyleneglycol
  • Lubrol PX
  • Monododecyl Ether, Nonaethyleneglycol
  • Monoether, Dodecyl Ethyleneglycol
  • Nonaethyleneglycol Monododecyl Ethers
  • Polyethylene Glycol 7 lauryl Ether
  • Polyethylene Glycol-7-lauryl Ethers
  • Polyoxyethylene 4 dodecyl Ether
  • Polyoxyethylene 9 lauryl Ether
  • Polyoxyethylene 9-lauryl Ethers
  • Polyoxyethylene Lauryl Ethers
  • Polyoxyethylenedodecyl Ethers
  • Tetraethyleneglycol Lauryl Ethers

MeSH Record

Aspects Covered

18 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

2019 (1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Polidocanol. Medical Subject Headings (MeSH). 2026. Unique ID D000077423. http://id.nlm.nih.gov/mesh/2026/D000077423
  2. Polidocanol. In: Wikipedia. https://en.wikipedia.org/wiki/Polidocanol
  3. Polidocanol. In: Wikidata. https://www.wikidata.org/wiki/Q377036
  4. Polidocanol. In: PubChem Compound. CID 656641. https://pubchem.ncbi.nlm.nih.gov/compound/656641