Chemicals and Drugs

Plasminogen Activator Inhibitor 1

A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • PAI-1
  • SERPINE1 Protein
  • Serpin E1
  • Type 1 Plasminogen Activator Inhibitor
  • E1, Serpin
  • Protein, SERPINE1

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

93; PAI-1 was see PLASMINOGEN INACTIVATORS 1990-92

MeSH Record

Previous Indexing

  • Plasminogen Inactivators (1990-1992)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.861w.695.500w
  2. D12.776w.124w.125.640w
  3. D12.776w.872w.695.500w
  4. D23.119.832.500w

AMA Style

References

  1. National Library of Medicine. Plasminogen Activator Inhibitor 1. Medical Subject Headings (MeSH). 2026. Unique ID D017395. http://id.nlm.nih.gov/mesh/2026/D017395
  2. Plasminogen Activator Inhibitor 1. In: Wikipedia. https://en.wikipedia.org/wiki/Plasminogen_activator_inhibitor-1
  3. Plasminogen Activator Inhibitor 1. In: Wikidata. https://www.wikidata.org/wiki/Q410485