Structured Summary
Abstract
A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Chemical Identity
Chemical Information
- Molecular Formula
- C13H19N5
- Molecular Weight
- 245.32 g/mol
- CAS Registry No.
- 113563-69-2
- IUPAC Name
- 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine
- InChIKey
- IVVNZDGDKPTYHK-UHFFFAOYSA-N
- SMILES
- CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1
- MeSH Unique ID
- D020110
- Source
- PubChem CID 4826
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- Pinacidil Anhydrous
- Pindac
- Anhydrous, Pinacidil
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
99; use PINACIDIL (NM) 1980-98
MeSH Record
Previous Indexing
- Guanidines (1983-1998)
- Pyridines (1980-1982)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Pinacidil. Medical Subject Headings (MeSH). 2026. Unique ID D020110. http://id.nlm.nih.gov/mesh/2026/D020110
- Pinacidil. In: Wikipedia. https://en.wikipedia.org/wiki/Pinacidil
- Pinacidil. In: Wikidata. https://www.wikidata.org/wiki/Q821869
- Pinacidil. In: PubChem Compound. CID 4826. https://pubchem.ncbi.nlm.nih.gov/compound/4826