Structured Summary
Abstract
An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
4 entry terms
- GTP-Dependent Phosphoenolpyruvate Carboxykinase
- Carboxykinase, GTP-Dependent Phosphoenolpyruvate
- GTP Dependent Phosphoenolpyruvate Carboxykinase
- Phosphoenolpyruvate Carboxykinase, GTP-Dependent
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not confuse with PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)
MeSH Record
History Note
98(73)
MeSH Record
Previous Indexing
- Carboxy-Lyases (1966-1972)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Phosphoenolpyruvate Carboxykinase (GTP). Medical Subject Headings (MeSH). 2026. Unique ID D010729. http://id.nlm.nih.gov/mesh/2026/D010729
- Phosphoenolpyruvate Carboxykinase (GTP). In: Wikipedia. https://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase
- Phosphoenolpyruvate Carboxykinase (GTP). In: Wikidata. https://www.wikidata.org/wiki/Q303568