Chemicals and Drugs

Phosphoenolpyruvate Carboxykinase (ATP)

An enzyme of the lyase class that catalyzes the conversion of ATP and oxaloacetate to ADP, phosphoenolpyruvate, and carbon dioxide. The enzyme is found in some bacteria, yeast, and Trypanosoma, and is important for the photosynthetic assimilation of carbon dioxide in some plants. EC 4.1.1.49.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme of the lyase class that catalyzes the conversion of ATP and oxaloacetate to ADP, phosphoenolpyruvate, and carbon dioxide. The enzyme is found in some bacteria, yeast, and Trypanosoma, and is important for the photosynthetic assimilation of carbon dioxide in some plants. EC 4.1.1.49.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • ATP-Dependent Phosphoenolpyruvate Carboxykinase
  • ATP Dependent Phosphoenolpyruvate Carboxykinase
  • Carboxykinase, ATP-Dependent Phosphoenolpyruvate
  • Phosphoenolpyruvate Carboxykinase, ATP-Dependent
  • T. cruzi PEPCK
  • Trypanosoma cruzi PEPCK
  • PEPCK, T. cruzi
  • PEPCK, Trypanosoma cruzi

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP)

MeSH Record

History Note

1998; use PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP) (NM) 1994-1997

MeSH Record

Previous Indexing

  • Phosphoenolpyruvate Carboxykinase (GTP) (1994-1997)

MeSH Hierarchy

Tree Number

  1. D08.811w.520w.224.125w.500w

AMA Style

References

  1. National Library of Medicine. Phosphoenolpyruvate Carboxykinase (ATP). Medical Subject Headings (MeSH). 2026. Unique ID D019764. http://id.nlm.nih.gov/mesh/2026/D019764
  2. Phosphoenolpyruvate Carboxykinase (ATP). In: Wikipedia. https://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP)
  3. Phosphoenolpyruvate Carboxykinase (ATP). In: Wikidata. https://www.wikidata.org/wiki/Q13362743