Chemicals and Drugs

Phleomycins

Water-soluble, copper-containing low molecular weight polypeptides obtained from the culture medium of Streptomyces verticillus. They are specific inhibitors of DNA synthesis in bacteria and have been found to act as antitumor agents. They have also been used against rust fungi of plants.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Water-soluble, copper-containing low molecular weight polypeptides obtained from the culture medium of Streptomyces verticillus. They are specific inhibitors of DNA synthesis in bacteria and have been found to act as antitumor agents. They have also been used against rust fungi of plants.

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Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Phleomycin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(81); was see under BLEOMYCINS 1981-90; was PHLEOMYCIN see under ANTIBIOTICS 1975-80

MeSH Record

Previous Indexing

  • Antibiotics (1971-1974)
  • Antibiotics, Antineoplastic (1971-1974)
  • Peptides (1971-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Phleomycins. Medical Subject Headings (MeSH). 2026. Unique ID D010692. http://id.nlm.nih.gov/mesh/2026/D010692
  2. Phleomycins. In: Wikipedia. https://en.wikipedia.org/wiki/Phleomycin
  3. Phleomycins. In: Wikidata. https://www.wikidata.org/wiki/Q16910345