Chemicals and Drugs

Phenylpropanolamine

A sympathomimetic that acts mainly by causing release of NOREPINEPHRINE but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sympathomimetic that acts mainly by causing release of NOREPINEPHRINE but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant.

Chemical Identity

Chemical Information

Molecular Formula
C9H13NO
Molecular Weight
151.21 g/mol
CAS Registry No.
37577-28-9
IUPAC Name
(1S,2R)-2-amino-1-phenylpropan-1-ol
InChIKey
DLNKOYKMWOXYQA-VXNVDRBHSA-N
SMILES
C[C@H]([C@H](C1=CC=CC=C1)O)N
MeSH Unique ID
D010665
Source
PubChem CID 26934

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Norephedrine
  • Dexatrim
  • Phenylpropanolamine Hydrochloride
  • Prolamine
  • Propagest
  • Triaminic DM
  • Hydrochloride, Phenylpropanolamine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

74(63); was see under SYMPATHOMIMETICS 1963-73

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Phenylpropanolamine. Medical Subject Headings (MeSH). 2026. Unique ID D010665. http://id.nlm.nih.gov/mesh/2026/D010665
  2. Phenylpropanolamine. In: Wikidata. https://www.wikidata.org/wiki/Q413147
  3. Phenylpropanolamine. In: PubChem Compound. CID 26934. https://pubchem.ncbi.nlm.nih.gov/compound/26934