Chemicals and Drugs

Phencyclidine Receptors

Specific sites or molecular structures on cell membranes or in cells with which phencyclidine reacts or to which it binds to elicit the specific response of the cell to phencyclidine. Studies have demonstrated the presence of multiple receptor sites for PCP. These are the PCP/sigma site, which binds both PCP and psychotomimetic opiates but not certain antipsychotics, and the PCP site, which selectively binds PCP analogs.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Specific sites or molecular structures on cell membranes or in cells with which phencyclidine reacts or to which it binds to elicit the specific response of the cell to phencyclidine. Studies have demonstrated the presence of multiple receptor sites for PCP. These are the PCP/sigma site, which binds both PCP and psychotomimetic opiates but not certain antipsychotics, and the PCP site, which selectively binds PCP analogs.

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Synonyms

7 entry terms
  • PCP Receptor
  • PCP Receptors
  • Phencylidine Receptor
  • Receptors, PCP
  • Receptors, Phencyclidine
  • Receptor, PCP
  • Receptor, Phencylidine

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Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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History Note

93; was PHENCYCLIDINE RECEPTOR (NM) 1981-92

MeSH Record

Previous Indexing

  • Receptors, Drug (1981-1983)
  • Receptors, Synaptic (1983-1992)

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References

  1. National Library of Medicine. Phencyclidine Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D017478. http://id.nlm.nih.gov/mesh/2026/D017478
  2. Phencyclidine Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q73593640