Chemicals and Drugs

Peroxiredoxins

A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.

MeSH Record

Classification

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MeSH Record

Synonyms

27 entry terms
  • Alkyl Hydroperoxide Reductase
  • Alkylhydroperoxide Reductase
  • Peroxidoxin
  • Peroxiredoxin
  • Protector Protein (Mixed-Function Oxidase Systems)
  • Thiol-Specific Antioxidant Protein
  • Thioredoxin Peroxidase
  • Hydroperoxide Reductase, Alkyl
  • Thiol Specific Antioxidant Protein
  • Alkyl Hydroperoxide Reductase C
  • Alkyl Hydroperoxide Reductase D
  • Peroxiredoxin 1
  • Peroxiredoxin 2
  • Peroxiredoxin 4
  • Peroxiredoxin 5
  • Peroxiredoxin I
  • Peroxiredoxin II
  • Peroxiredoxin IV
  • Peroxiredoxin V
  • Peroxiredoxin-4
  • Thioredoxin Peroxidase 1
  • Thioredoxin Peroxidase 2
  • Thioredoxin Peroxidase PMP20
  • Thioredoxin-Dependent Peroxide Reductase 1
  • Thioredoxin-Dependent Peroxide Reductase 2
  • Thioredoxin Dependent Peroxide Reductase 1
  • Thioredoxin Dependent Peroxide Reductase 2

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1988)

MeSH Hierarchy

Tree Number

  1. D08.811w.682w.732w.850w

AMA Style

References

  1. National Library of Medicine. Peroxiredoxins. Medical Subject Headings (MeSH). 2026. Unique ID D054464. http://id.nlm.nih.gov/mesh/2026/D054464
  2. Peroxiredoxins. In: Wikipedia. https://en.wikipedia.org/wiki/Peroxiredoxin
  3. Peroxiredoxins. In: Wikidata. https://www.wikidata.org/wiki/Q419462