Structured Summary
Abstract
A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
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Classification
Broader headings
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Synonyms
8 entry terms
- EF-Tu
- Elongation Factor Tu
- Protein Synthesis Elongation Factor Tu
- EF Tu
- Factor Tu, Elongation
- Eucaryotic Elongation Factor Tu
- eEF-Tu
- eEF Tu
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
coordinate with MITOCHONDRIAL PROTEINS or BACTERIAL PROTEINS if pertinent
MeSH Record
History Note
86
MeSH Record
Previous Indexing
- Bacterial Proteins (1966-1972)
- Peptide Elongation Factors (1973-1985)
- Peptides (1966-1972)
- Proteins (1966-1972)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Peptide Elongation Factor Tu. Medical Subject Headings (MeSH). 2026. Unique ID D010444. http://id.nlm.nih.gov/mesh/2026/D010444
- Peptide Elongation Factor Tu. In: Wikipedia. https://en.wikipedia.org/wiki/EF-Tu
- Peptide Elongation Factor Tu. In: Wikidata. https://www.wikidata.org/wiki/Q24726678