Structured Summary
Abstract
Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
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Classification
Broader headings
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Synonyms
17 entry terms
- EF 1
- EF-1
- EF-1H
- Elongation Factor 1
- EF 1H
- EF-1alpha
- EF-1beta
- EF-1delta
- EF-1gamma
- Elongation Factor 1alpha
- Elongation Factor 1beta
- Elongation Factor 1delta
- Elongation Factor 1gamma
- EF 1alpha
- EF 1beta
- EF 1delta
- EF 1gamma
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2000; for ELONGATION FACTOR 1 use PEPTIDE ELONGATION FACTOR 1 (NM) 1980-1999; for ELONGATION FACTOR 1GAMMA use PEPTIDE ELONGATION FACTOR 1 (NM) 1994-1999
MeSH Record
Previous Indexing
- Peptide Elongation Factors (1973-1999)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Peptide Elongation Factor 1. Medical Subject Headings (MeSH). 2026. Unique ID D020648. http://id.nlm.nih.gov/mesh/2026/D020648
- Peptide Elongation Factor 1. In: Wikidata. https://www.wikidata.org/wiki/Q66660235