Chemicals and Drugs

Peptaibols

A group of peptides characterized by length of 1-2 dozen residues with a high proportion of them being non-proteinogenic, notably alpha-aminoisobutyric acid (Aib) and isovaline, and have a C-terminal amino alcohol and N terminal alkyl group. They are found in FUNGI and some are ANTI-INFECTIVE AGENTS. They form channels or pores in target organisms. The term is a contraction of peptide-Aib-alcohol.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of peptides characterized by length of 1-2 dozen residues with a high proportion of them being non-proteinogenic, notably alpha-aminoisobutyric acid (Aib) and isovaline, and have a C-terminal amino alcohol and N terminal alkyl group. They are found in FUNGI and some are ANTI-INFECTIVE AGENTS. They form channels or pores in target organisms. The term is a contraction of peptide-Aib-alcohol.

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Synonyms

11 entry terms
  • Peptaibol
  • Alamethicins
  • Antiamoebins
  • Atroviridins
  • Chrysospermins
  • Culicinins
  • Emerimicin
  • Emerimicins
  • Trichorzianines
  • Zervamicin
  • Zervamicins

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2008; for EMERIMICINS use PEPTIDES 1977-2007

MeSH Record

Previous Indexing

  • Peptides (1977-2007)

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References

  1. National Library of Medicine. Peptaibols. Medical Subject Headings (MeSH). 2026. Unique ID D054848. http://id.nlm.nih.gov/mesh/2026/D054848
  2. Peptaibols. In: Wikipedia. https://en.wikipedia.org/wiki/Peptaibol
  3. Peptaibols. In: Wikidata. https://www.wikidata.org/wiki/Q7166514