Structured Summary
Abstract
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
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See Also
MeSH Record
Synonyms
3 entry terms
- Pepsin
- Pepsin 1
- Pepsin 3
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/biosyn /physiol permitted
MeSH Record
History Note
91; was PEPSIN 1964-90
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 66
AMA Style
References
- National Library of Medicine. Pepsin A. Medical Subject Headings (MeSH). 2026. Unique ID D010434. http://id.nlm.nih.gov/mesh/2026/D010434
- Pepsin A. In: Wikipedia. https://en.wikipedia.org/wiki/Pepsin_A
- Pepsin A. In: Wikidata. https://www.wikidata.org/wiki/Q12856816