Chemicals and Drugs

Peplomycin

An antineoplastic agent derived from BLEOMYCIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antineoplastic agent derived from BLEOMYCIN.

Chemical Identity

Chemical Information

Molecular Formula
C61H88N18O21S2
Molecular Weight
1473.6 g/mol
CAS Registry No.
68247-85-8
IUPAC Name
[(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-oxo-1-[2-[4-[4-[3-[[(1S)-1-phenylethyl]amino]propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]butan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
InChIKey
QIMGFXOHTOXMQP-GFAGFCTOSA-N
SMILES
CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCN[C@@H](C)C7=CC=CC=C7)O
MeSH Unique ID
D017663
Source
PubChem CID 6852373

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Pepleomycin
  • NK-631
  • Peplomycin Sulfate
  • Peplomycin Sulfate (1:1)
  • NK 631
  • NK631
  • Sulfate, Peplomycin

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

94; was PEPLEOMYCIN (NM) 1979-93

MeSH Record

Previous Indexing

  • Bleomycins (1979-1993)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.420w.110w.690
  2. D12.644w.233w.110w.690

AMA Style

References

  1. National Library of Medicine. Peplomycin. Medical Subject Headings (MeSH). 2026. Unique ID D017663. http://id.nlm.nih.gov/mesh/2026/D017663
  2. Peplomycin. In: Wikidata. https://www.wikidata.org/wiki/Q27261405
  3. Peplomycin. In: PubChem Compound. CID 6852373. https://pubchem.ncbi.nlm.nih.gov/compound/6852373