Chemicals and Drugs

Pentoxyl

5-Hydroxymethyl-6-methyl- 2,4-(1H,3H)-pyrimidinedione. Uracil derivative used in combination with toxic antibiotics to lessen their toxicity; also to stimulate leukopoiesis and immunity. Synonyms: pentoksil; hydroxymethylmethyluracil.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

5-Hydroxymethyl-6-methyl- 2,4-(1H,3H)-pyrimidinedione. Uracil derivative used in combination with toxic antibiotics to lessen their toxicity; also to stimulate leukopoiesis and immunity. Synonyms: pentoksil; hydroxymethylmethyluracil.

Chemical Identity

Chemical Information

Molecular Formula
C6H8N2O3
Molecular Weight
156.14 g/mol
CAS Registry No.
147-61-5
IUPAC Name
5-(hydroxymethyl)-6-methyl-1H-pyrimidine-2,4-dione
InChIKey
XBAVGYMDOXCWQU-UHFFFAOYSA-N
SMILES
CC1=C(C(=O)NC(=O)N1)CO
MeSH Unique ID
D010432
Source
PubChem CID 8983

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(80); was see under URACIL 1980-90

MeSH Record

Previous Indexing

  • Uracil (1966-1974) /AA (1975-1979)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Pentoxyl. Medical Subject Headings (MeSH). 2026. Unique ID D010432. http://id.nlm.nih.gov/mesh/2026/D010432
  2. Pentoxyl. In: Wikidata. https://www.wikidata.org/wiki/Q27268517
  3. Pentoxyl. In: PubChem Compound. CID 8983. https://pubchem.ncbi.nlm.nih.gov/compound/8983