Phenomena and Processes

Pentose Phosphate Pathway

An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.

MeSH Record

Classification

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MeSH Record

Synonyms

27 entry terms
  • Hexose Monophosphate Shunt
  • Pentose Phosphate Shunt
  • Pentose Shunt
  • Pentose-Phosphate Pathway
  • Pentosephosphate Pathway
  • Pentosephosphate Shunt
  • Hexose Monophosphate Shunts
  • Pathway, Pentose Phosphate
  • Pathway, Pentose-Phosphate
  • Pathway, Pentosephosphate
  • Pathways, Pentose Phosphate
  • Pathways, Pentose-Phosphate
  • Pathways, Pentosephosphate
  • Pentose Phosphate Pathways
  • Pentose Phosphate Shunts
  • Pentose Shunts
  • Pentose-Phosphate Pathways
  • Pentosephosphate Pathways
  • Pentosephosphate Shunts
  • Shunt, Hexose Monophosphate
  • Shunt, Pentose
  • Shunt, Pentose Phosphate
  • Shunt, Pentosephosphate
  • Shunts, Hexose Monophosphate
  • Shunts, Pentose
  • Shunts, Pentose Phosphate
  • Shunts, Pentosephosphate

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2006 (1985)

MeSH Record

Previous Indexing

  • Hexosephosphates (1966-1984)
  • Pentosephosphates (1966-1984)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 75

AMA Style

References

  1. National Library of Medicine. Pentose Phosphate Pathway. Medical Subject Headings (MeSH). 2026. Unique ID D010427. http://id.nlm.nih.gov/mesh/2026/D010427
  2. Pentose Phosphate Pathway. In: Wikipedia. https://en.wikipedia.org/wiki/Pentose_phosphate_pathway
  3. Pentose Phosphate Pathway. In: Wikidata. https://www.wikidata.org/wiki/Q827489