Chemicals and Drugs

Pentagastrin

A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.

Chemical Identity

Chemical Information

Molecular Formula
C37H49N7O9S
Molecular Weight
767.9 g/mol
CAS Registry No.
5534-95-2
IUPAC Name
(3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid
InChIKey
NEYNJQRKHLUJRU-DZUOILHNSA-N
SMILES
CC(C)(C)OC(=O)NCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N
MeSH Unique ID
D010418
Source
PubChem CID 9853654

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

4 entry terms
  • Gastrin Pentapeptide
  • Pentapeptide, Gastrin
  • Acignost
  • Peptavlon

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73(72)

MeSH Record

Previous Indexing

  • Gastrointestinal Hormones (1966-1971)
  • Peptides (1966-1971)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.317w.413.593w
  2. D12.644w.456w.716w

AMA Style

References

  1. National Library of Medicine. Pentagastrin. Medical Subject Headings (MeSH). 2026. Unique ID D010418. http://id.nlm.nih.gov/mesh/2026/D010418
  2. Pentagastrin. In: Wikipedia. https://en.wikipedia.org/wiki/Pentagastrin
  3. Pentagastrin. In: Wikidata. https://www.wikidata.org/wiki/Q423586
  4. Pentagastrin. In: PubChem Compound. CID 9853654. https://pubchem.ncbi.nlm.nih.gov/compound/9853654