Chemicals and Drugs

Penicillin-Binding Proteins

Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin-binding proteins are primarily enzymes involved in CELL WALL biosynthesis including MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PEPTIDE SYNTHASES; TRANSPEPTIDASES; and HEXOSYLTRANSFERASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin-binding proteins are primarily enzymes involved in CELL WALL biosynthesis including MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PEPTIDE SYNTHASES; TRANSPEPTIDASES; and HEXOSYLTRANSFERASES.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

31 entry terms
  • Penicillin-Binding Protein
  • Penicillin Binding Protein
  • Penicillin Binding Proteins
  • Proteins, Penicillin-Binding
  • Penicillin-Binding Protein 1
  • Penicillin-Binding Protein 1A
  • Penicillin-Binding Protein 1b
  • Penicillin-Binding Protein 2
  • Penicillin-Binding Protein 2a
  • Penicillin-Binding Protein 2b
  • Penicillin-Binding Protein 3
  • Penicillin-Binding Protein 4
  • Penicillin-Binding Protein 5
  • Penicillin-Binding Protein 6
  • Penicillin-Binding Protein 7
  • Penicillin-Binding Protein-2a
  • Peptidoglycan Synthetase
  • Penicillin Binding Protein 1
  • Penicillin Binding Protein 1A
  • Penicillin Binding Protein 1b
  • Penicillin Binding Protein 2
  • Penicillin Binding Protein 2a
  • Penicillin Binding Protein 2b
  • Penicillin Binding Protein 3
  • Penicillin Binding Protein 4
  • Penicillin Binding Protein 5
  • Penicillin Binding Protein 6
  • Penicillin Binding Protein 7
  • Protein 1A, Penicillin-Binding
  • Protein 1b, Penicillin-Binding
  • Synthetase, Peptidoglycan

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005 (1978);

MeSH Record

Previous Indexing

  • Bacterial Proteins (1978-2004)
  • Carrier Proteins (1978-2004)
  • Hexosyltransferases (1999-2004)
  • Muramoylpentapeptide Carboxypeptidase (1978-2004)
  • Peptidyltransferase (1978-2004)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Penicillin-Binding Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D046915. http://id.nlm.nih.gov/mesh/2026/D046915
  2. Penicillin-Binding Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Penicillin-binding_proteins
  3. Penicillin-Binding Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q7162855