Structured Summary
Abstract
Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Chemical Identity
Chemical Information
- Molecular Formula
- C28H38N4O8
- Molecular Weight
- 558.6 g/mol
- CAS Registry No.
- 23668-11-3
- IUPAC Name
- [(1S,2R,3R,4S,5S)-5-(3-acetylanilino)-4-amino-3-(dimethylcarbamoylamino)-1,2-dihydroxy-3-[(1S)-1-hydroxyethyl]-2-methylcyclopentyl]methyl 2-hydroxy-6-methylbenzoate
- InChIKey
- WVIUOSJLUCTGFK-JUJPXXQGSA-N
- SMILES
- CC1=C(C(=CC=C1)O)C(=O)OC[C@]2([C@H]([C@@H]([C@]([C@@]2(C)O)([C@H](C)O)NC(=O)N(C)C)N)NC3=CC=CC(=C3)C(=O)C)O
- MeSH Unique ID
- D010142
- Source
- PubChem CID 5289124
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
MeSH Record
Previous Indexing
- Antibiotics, Antineoplastic (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Pactamycin. Medical Subject Headings (MeSH). 2026. Unique ID D010142. http://id.nlm.nih.gov/mesh/2026/D010142
- Pactamycin. In: Wikidata. https://www.wikidata.org/wiki/Q27252022
- Pactamycin. In: PubChem Compound. CID 5289124. https://pubchem.ncbi.nlm.nih.gov/compound/5289124