Structured Summary
Abstract
An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.
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Synonyms
9 entry terms
- PSF Splicing Factor
- Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
- SFPQ Protein
- Splicing Factor Proline-Glutamine Rich Protein
- PTB Associated Splicing Factor
- Polypyrimidine Tract Binding Protein Associated Splicing Factor
- Splicing Factor Proline Glutamine Rich Protein
- Splicing Factor, PSF
- Splicing Factor, PTB-Associated
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1993)
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AMA Style
References
- National Library of Medicine. PTB-Associated Splicing Factor. Medical Subject Headings (MeSH). 2026. Unique ID D000072670. http://id.nlm.nih.gov/mesh/2026/D000072670
- PTB-Associated Splicing Factor. In: Wikidata. https://www.wikidata.org/wiki/Q21114335