Chemicals and Drugs

POU Domain Factors

A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.

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Classification

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Synonyms

5 entry terms
  • POU Proteins
  • Pit-Oct-Unc Proteins
  • Transcription Factor POU
  • POU, Transcription Factor
  • Pit Oct Unc Proteins

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1992)

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AMA Style

References

  1. National Library of Medicine. POU Domain Factors. Medical Subject Headings (MeSH). 2026. Unique ID D050809. http://id.nlm.nih.gov/mesh/2026/D050809
  2. POU Domain Factors. In: Wikidata. https://www.wikidata.org/wiki/Q78184975