Chemicals and Drugs

Oxythiamine

Thiamine antagonist, antimetabolite.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Thiamine antagonist, antimetabolite.

Chemical Identity

Chemical Information

Molecular Formula
C12H16N3O2S+
Molecular Weight
266.34 g/mol
CAS Registry No.
136-16-3
IUPAC Name
5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one
InChIKey
SRDGSXVLAVRBLU-UHFFFAOYSA-O
SMILES
CC1=C(SC=[N+]1CC2=CN=C(NC2=O)C)CCO
MeSH Unique ID
D010119
Source
PubChem CID 8682

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Hydroxythiamine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a thiamine antag

MeSH Record

History Note

91(75); was see under THIAZOLES 1975-90

MeSH Record

Previous Indexing

  • Pyrimidines (1974)
  • Thiazoles (1970-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.886w.675.540w
  2. D03w.383.129w.708.540w

AMA Style

References

  1. National Library of Medicine. Oxythiamine. Medical Subject Headings (MeSH). 2026. Unique ID D010119. http://id.nlm.nih.gov/mesh/2026/D010119
  2. Oxythiamine. In: Wikipedia. https://en.wikipedia.org/wiki/Oxythiamine
  3. Oxythiamine. In: Wikidata. https://www.wikidata.org/wiki/Q27147706
  4. Oxythiamine. In: PubChem Compound. CID 8682. https://pubchem.ncbi.nlm.nih.gov/compound/8682