Chemicals and Drugs

Oxcarbazepine

A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.

Chemical Identity

Chemical Information

Molecular Formula
C15H12N2O2
Molecular Weight
252.27 g/mol
CAS Registry No.
28721-07-5
IUPAC Name
5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
InChIKey
CTRLABGOLIVAIY-UHFFFAOYSA-N
SMILES
C1C2=CC=CC=C2N(C3=CC=CC=C3C1=O)C(=O)N
MeSH Unique ID
D000078330
Source
PubChem CID 34312

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
  • GP 47680
  • Timox
  • Trileptal

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1982)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Oxcarbazepine. Medical Subject Headings (MeSH). 2026. Unique ID D000078330. http://id.nlm.nih.gov/mesh/2026/D000078330
  2. Oxcarbazepine. In: Wikipedia. https://en.wikipedia.org/wiki/Oxcarbazepine
  3. Oxcarbazepine. In: Wikidata. https://www.wikidata.org/wiki/Q176301
  4. Oxcarbazepine. In: PubChem Compound. CID 34312. https://pubchem.ncbi.nlm.nih.gov/compound/34312