Chemicals and Drugs

Orotidine-5'-Phosphate Decarboxylase

Orotidine-5'-phosphate carboxy-lyase. Catalyzes the decarboxylation of orotidylic acid to yield uridylic acid in the final step of the pyrimidine nucleotide biosynthesis pathway. EC 4.1.1.23.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Orotidine-5'-phosphate carboxy-lyase. Catalyzes the decarboxylation of orotidylic acid to yield uridylic acid in the final step of the pyrimidine nucleotide biosynthesis pathway. EC 4.1.1.23.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

13 entry terms
  • OMP Decarboxylase
  • Orotidine 5 Phosphate Decarboxylase
  • Orotidine 5' Phosphate Decarboxylase
  • Orotidine Phosphate Carboxy-Lyase
  • Orotidine-5-Phosphate Decarboxylase
  • Orotidylate Decarboxylase
  • Carboxy-Lyase, Orotidine Phosphate
  • Decarboxylase, OMP
  • Decarboxylase, Orotidine-5'-Phosphate
  • Decarboxylase, Orotidine-5-Phosphate
  • Decarboxylase, Orotidylate
  • Orotidine Phosphate Carboxy Lyase
  • Phosphate Carboxy-Lyase, Orotidine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic: consider also OROTIC ACID /urine (IM) and PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM)

MeSH Record

History Note

91(77); was see under CARBOXY-LYASES 1977-90

MeSH Record

Previous Indexing

  • Carboxy-Lyases (1966-1976)
  • Pyrimidine Nucleotides (1973-1974)
  • Ribonucleotides (1973-1974)
  • Uracil Nucleotides (1975-1976)

MeSH Hierarchy

Tree Number

  1. D08.811w.520w.224.125w.450w

AMA Style

References

  1. National Library of Medicine. Orotidine-5'-Phosphate Decarboxylase. Medical Subject Headings (MeSH). 2026. Unique ID D009964. http://id.nlm.nih.gov/mesh/2026/D009964
  2. Orotidine-5'-Phosphate Decarboxylase. In: Wikipedia. https://en.wikipedia.org/wiki/Orotidine_5%E2%80%B2-phosphate_decarboxylase
  3. Orotidine-5'-Phosphate Decarboxylase. In: Wikidata. https://www.wikidata.org/wiki/Q7103879