Chemicals and Drugs

Ornipressin

A synthetic analog of vasopressin with ORNITHINE substitution at residue 8 of the cyclic nonapeptide. It is used as a local vasoconstrictor and hemostatic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic analog of vasopressin with ORNITHINE substitution at residue 8 of the cyclic nonapeptide. It is used as a local vasoconstrictor and hemostatic.

Chemical Identity

Chemical Information

Molecular Formula
C45H63N13O12S2
Molecular Weight
1042.2 g/mol
CAS Registry No.
3397-23-7
IUPAC Name
(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
InChIKey
MUNMIGOEDGHVLE-LGYYRGKSSA-N
SMILES
C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N
MeSH Unique ID
D009951
Source
PubChem CID 14257660

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Ornithine Vasopressin
  • Ornithine-8-Vasopressin
  • Orpressin
  • Vasopressin, Ornithine
  • Ornithine 8 Vasopressin
  • POR-8

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under VASOPRESSINS 1979-90

MeSH Record

Previous Indexing

  • Ornithine (1966-1978)
  • Vasopressins (1966-1978)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.631.692.781.700w
  2. D12.644w.400w.900.700w
  3. D12.644w.456w.925.700w
  4. D12.644w.548w.691.692.781.700w
  5. D12.776w.631w.650w.937.700w

AMA Style

References

  1. National Library of Medicine. Ornipressin. Medical Subject Headings (MeSH). 2026. Unique ID D009951. http://id.nlm.nih.gov/mesh/2026/D009951
  2. Ornipressin. In: Wikipedia. https://en.wikipedia.org/wiki/Ornipressin
  3. Ornipressin. In: Wikidata. https://www.wikidata.org/wiki/Q3038432
  4. Ornipressin. In: PubChem Compound. CID 14257660. https://pubchem.ncbi.nlm.nih.gov/compound/14257660