Chemicals and Drugs

Omeprazole

A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Chemical Identity

Chemical Information

Molecular Formula
C17H19N3O3S
Molecular Weight
345.4 g/mol
CAS Registry No.
73590-58-6
IUPAC Name
6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-benzimidazole
InChIKey
SUBDBMMJDZJVOS-UHFFFAOYSA-N
SMILES
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
MeSH Unique ID
D009853
Source
PubChem CID 4594

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • H 168-68
  • Omeprazole Magnesium
  • Omeprazole Sodium
  • Prilosec
  • H 168 68
  • H 16868
  • Magnesium, Omeprazole
  • Sodium, Omeprazole

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1987

MeSH Record

Previous Indexing

  • Benzimidazoles (1966-1986)

MeSH Hierarchy

Tree Numbers

  1. D02w.886w.640w.074.500w
  2. D03w.383.725w.024.500w
  3. D03w.633.100.103.034.500w

MeSH Record

NLM Classification

QV 69

AMA Style

References

  1. National Library of Medicine. Omeprazole. Medical Subject Headings (MeSH). 2026. Unique ID D009853. http://id.nlm.nih.gov/mesh/2026/D009853
  2. Omeprazole. In: Wikipedia. https://en.wikipedia.org/wiki/Omeprazole
  3. Omeprazole. In: Wikidata. https://www.wikidata.org/wiki/Q422210
  4. Omeprazole. In: PubChem Compound. CID 4594. https://pubchem.ncbi.nlm.nih.gov/compound/4594