Structured Summary
Abstract
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
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Drug Class
Pharmacological Action
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Synonyms
1 entry terms
- Oligomycin
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Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
82; was OLIGOMYCIN 1963-81 (Prov 1963-65)
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References
- National Library of Medicine. Oligomycins. Medical Subject Headings (MeSH). 2026. Unique ID D009840. http://id.nlm.nih.gov/mesh/2026/D009840
- Oligomycins. In: Wikipedia. https://en.wikipedia.org/wiki/Oligomycin
- Oligomycins. In: Wikidata. https://www.wikidata.org/wiki/Q1076381