Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Off-Label Use

The practice of prescribing or using a drug or a vaccine outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The practice of prescribing or using a drug or a vaccine outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

16 entry terms
  • Off-Label Prescribing
  • Unlabeled Indication
  • Indication, Unlabeled
  • Off Label Prescribing
  • Off Label Use
  • Off-Label Prescribings
  • Off-Label Uses
  • Prescribing, Off-Label
  • Unlabeled Indications
  • Dose-Sparing Drug Use
  • Fractional Dose Drug Use
  • Reduced-Dose Drug Use
  • Dose Sparing Drug Use
  • Dose-Sparing Drug Uses
  • Reduced Dose Drug Use
  • Reduced-Dose Drug Uses

MeSH Record

Aspects Covered

9 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, legislation & jurisprudence, nursing, standards, statistics & numerical data, veterinary.

MeSH Record

Indexing Annotation

do not confuse with DRUG REPOSITIONING

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Drug Labeling (2008-2009)
  • Drug Prescriptions (2008-2009)

MeSH Hierarchy

Tree Number

  1. E02w.319w.307.500w

AMA Style

References

  1. National Library of Medicine. Off-Label Use. Medical Subject Headings (MeSH). 2026. Unique ID D056687. http://id.nlm.nih.gov/mesh/2026/D056687
  2. Off-Label Use. In: Wikipedia. https://en.wikipedia.org/wiki/Off-label_use
  3. Off-Label Use. In: Wikidata. https://www.wikidata.org/wiki/Q119697