Structured Summary
Abstract
A potent, long-acting synthetic SOMATOSTATIN octapeptide analog that inhibits secretion of GROWTH HORMONE and is used to treat hormone-secreting tumors; DIABETES MELLITUS; HYPOTENSION, ORTHOSTATIC; HYPERINSULINISM; hypergastrinemia; and small bowel fistula.
Chemical Identity
Chemical Information
- Molecular Formula
- C49H66N10O10S2
- Molecular Weight
- 1019.2 g/mol
- CAS Registry No.
- 83150-76-9
- IUPAC Name
- (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
- InChIKey
- DEQANNDTNATYII-OULOTJBUSA-N
- SMILES
- C[C@H]([C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)[C@@H](CC5=CC=CC=C5)N)C(=O)N[C@H](CO)[C@@H](C)O)O
- MeSH Unique ID
- D015282
- Source
- PubChem CID 448601
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
19 entry terms
- Compound 201-995
- Octreotide Acetate
- Octreotide Acetate Salt
- SAN 201-995
- SM 201-995
- SMS 201-995
- Sandostatin
- Sandostatine
- Sandoz 201-995
- Compound 201 995
- Compound 201995
- SAN 201 995
- SAN 201995
- SM 201 995
- SM 201995
- SMS 201 995
- SMS 201995
- Sandoz 201 995
- Sandoz 201995
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
89
MeSH Record
Previous Indexing
- Antineoplastic Agents (1982-1988)
- Somatostatin/analogs & derivatives (1982-1988)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Octreotide. Medical Subject Headings (MeSH). 2026. Unique ID D015282. http://id.nlm.nih.gov/mesh/2026/D015282
- Octreotide. In: Wikipedia. https://en.wikipedia.org/wiki/Octreotide
- Octreotide. In: Wikidata. https://www.wikidata.org/wiki/Q419935
- Octreotide. In: PubChem Compound. CID 448601. https://pubchem.ncbi.nlm.nih.gov/compound/448601