Chemicals and Drugs

O-Acetyl-ADP-Ribose

An acetyl ester of ADENOSINE DIPHOSPHATE RIBOSE formed during NAD-dependent deacetylation of proteins by SIRTUINS. The acetate group resides on the ribose ring where nicotinamide was cleaved from NAD during the reaction. Several isomers of O-acetyl-ADP-ribose have been isolated from the reaction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An acetyl ester of ADENOSINE DIPHOSPHATE RIBOSE formed during NAD-dependent deacetylation of proteins by SIRTUINS. The acetate group resides on the ribose ring where nicotinamide was cleaved from NAD during the reaction. Several isomers of O-acetyl-ADP-ribose have been isolated from the reaction.

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Classification

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MeSH Record

Synonyms

7 entry terms
  • AADPR
  • Adenosine-Diphosphate-Ribose, O-Acetyl-
  • O-Acetyl-Adenosine-Diphosphate-Ribose
  • Adenosine Diphosphate Ribose, O Acetyl
  • O Acetyl ADP Ribose
  • O Acetyl Adenosine Diphosphate Ribose
  • O-Acetyl- Adenosine-Diphosphate-Ribose

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2003; use O-ACETYL-ADP-RIBOSE (NM) 2001-2002

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. O-Acetyl-ADP-Ribose. Medical Subject Headings (MeSH). 2026. Unique ID D038961. http://id.nlm.nih.gov/mesh/2026/D038961
  2. O-Acetyl-ADP-Ribose. In: Wikidata. https://www.wikidata.org/wiki/Q67734111