Chemicals and Drugs

Notch4 Receptor

A notch receptor and proto-oncogene protein characterized by a large extracellular domain that consists of 29 EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats) and five ANKYRIN REPEATS. It functions as a receptor for SERRATE-JAGGED PROTEINS and Delta1 (DLK1) protein to control cell fate determination.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A notch receptor and proto-oncogene protein characterized by a large extracellular domain that consists of 29 EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats) and five ANKYRIN REPEATS. It functions as a receptor for SERRATE-JAGGED PROTEINS and Delta1 (DLK1) protein to control cell fate determination.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • Notch-4 Protein
  • Notch-4 Receptor
  • Notch4 Protein
  • Receptor, Notch4
  • Notch 4 Protein
  • Notch 4 Receptor
  • Receptor, Notch-4

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Proto-Oncogene Proteins (1992-2017)
  • Receptors, Notch (2006-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.725.937
  2. D12.776w.624.664.700.815
  3. D12.776w.930w.770.937

AMA Style

References

  1. National Library of Medicine. Notch4 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D000074562. http://id.nlm.nih.gov/mesh/2026/D000074562
  2. Notch4 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q24783380